Can you change the compression level to thin-provisioned (basic compression)?
Note: Thick-provisioned (no compression) with NFC was not blocked in Thinware vBackup 4.0.x, however due to limitations in VMware Virtual Disk Manager this often resulted in error (error documented here). Because of this, this configuration (no compression with NFC) is not allowed in Thinware vBackup 5.0.0.